Center Announcements

Past Seminars


2012 – 2013

*All seminars are on Tuesdays at 5:00PM in Weiss 305 unless otherwise noted.

September 18, 2012
"New receptors for old viruses: from pathogens to cancer therapeutics"
Roberto Cattaneo, PhD.
Mayo Clinic

October 31, 2012
CANCELED
Sharookh Kapadia, PhD.
Genentech

November 6, 2012
"From genetics to translational genomics of HCV clearance – dealing with the new players in the game"
Ludmila Prokunina-Olsson, PhD.
NCI-NIH

November 20, 2012
"Host genetic variation and the HCV replication cycle"
Thomas von Hahn, MD
Medizinische Hochschule Hannover

January 8, 2013
"Integrating induced pluripotent stem cells and technology to build hepatic model systems"
Robert Schwartz, MD, PhD
MIT

January 22, 2013
"HCV and IL28B genetic polymorphisms: Have we learned anything yet?"
Susanna Naggie, MD
Duke Clinical Research Institute

February 5, 2013
"Lipid blueprints for viral replication derive from endocytic rewiring of cellular cholesterol landscape"
Nihal Altan-Bonnet, PhD
Rutgers University – Newark

February 19, 2013
"Virus-specific antibodies inhibit inflammasome activation in chronic viral infection"
Andrea Cox, MD, PhD
Johns Hopkins Universityy

March 5, 2013
"Importance of resistance to antiviral treatment of chronic hepatitis C"
Christoph Sarrazin, MD
Goethe-University Hospital Frankfurt

March 19, 2013
"Rotavirus: host range, pathogenesis & innate immunity a ménage a trois"
Harry Greenberg, MD
Stanford University School of Medicine

April 2, 2013
"The causes, detection and impact of liver fibrosis in hepatitis C"
William Rosenberg, MA, MBBS, DPhil, FRCP
UCL School of Life and Medical Sciences

April 16, 2013
"Modeling HCV infection: from sequences to drug therapy"
Alan Perelson, PhD
Los Alamos National Laboratory – CETI

April 30, 2013
"Acute liver failure 2012: It's not all viruses"
William Lee, MD
Southwestern Medical Center

May 21, 2013
CANCELED
"Suppressing diversity in RNA viruses"
Karla Kirkegaard, PhD
Stanford University School of Medicine

2011 – 2012

*All seminars are on Tuesdays at 5:00PM in Weiss 305 unless otherwise noted.

October 4, 2011
"Insights into hepatitis C virus infection and pathogenesis from studies of infected donors and recipients"
Michael P. Busch, MD, PhD
Blood Systems Research Institute

November 1, 2011
"Discovery of Telaprevir - A novel protease inhibitor for the treatment of hepatitis C virus infection"
Ann D. Kwong, PhD
Vertex Pharmaceuticals, Inc.

November 9, 2011 - Wednesday
"Structure and function of hepatitis C virus nonstructural protein 4B"
Darius Moradpour, MD
University of Lausanne

November 15, 2011
"Cellular cofactors and culture systems for HCV infection"
Hengli Tang, PhD
Florida State University

November 29, 2011
"Role of genetic variation in host factors for HCV infection"
Thomas von Hahn, MD
Hannover Medical School

January 17, 2012
"Masking of the HCV genome by liver-specific microRNA complexes"
Peter Sarnow, PhD
Stanford University

January 31, 2012
"Race and ethnicity in HCV"
Andrew J. Muir, MD, MHS
Duke University

February 28, 2012
"Novel antiviral strategies targeting hepatitis C virus entry factors"
Thomas Baumert, MD
Duke University

March 13, 2012 - Weiss 301
"Pluripotent Stem Cells as a Model of Human Liver Development and Disease"
Stephen Duncan, D. Phil.
Medical College of Wisconsin

March 27, 2012
"Hepatitis C virus genotypes and studies in novel culture systems"
Jens Bukh, MD
University of Copenhagen

April 24, 2012
"Antiviral and autoimmune antibodies elicited in hepatitis C virus infection"
Mansun Law, D.Phil.
The Scripps Research Institute

May 8, 2012
"RNA virus diversity, adaptation and pathogenesis"
Raul Andino, PhD
University of California, San Francisco

May 22, 2012
"Hepatitis C virus deletion mutants in chronic HCV infection and their role in liver disease severity"
Raffaele De Francesco, PhD
Istituto Nazionale di Genetica Moleculare

2010 – 2011

"Improving interferon: Not all supplements are the SAMe"
Jordan Feld, MD, MPH
Toronto Western Hospital Liver Centre

"Modulating vaccine responses with innate immunity"
Bali Pulendran, PhD
Emory Vaccine Center

"Human liver chimeric mice in biomedical research"
Karl-Dimiter Bissig, MD, PhD
The Salk Institute

"Identification and characterization of transmitted HCV genomes in humans with acute infection"
George M Shaw, MD, PhD
University of Alabama at Birmingham

"Fidelity of HCV NS5B and implications for the development of drug resistance"
Matthias Gotte, PhD
McGill University, Canada

"Pharmacogenetics, hepatitis C, clinical trials and drug development"
John McHutchison, MD
Gilead Sciences

"Viral and cellular determinants of hepatitis C virus infection and replication"
George Luo, MD, MPH
University of Kentucky College of Medicine

"The role of miR-122 and RISC proteins in promoting HCV growth"
Joyce Wilson, PhD
University of Saskatchewan

"Identification of host factors required for HCV infection and their utility as antiviral drug targets"
Susan Uprichard, PhD
The University of Illinois at Chicago

"Ribavirin uptake as a determinant of hepatitis C virus treatment response"
Julie Pfeiffer, PhD
University of Texas Southwestern Medical Center

"Use of biomarker and immune signatures in the conduct of clinical trials of MVA-based therapeutic vaccines for the treatment of non small cell lung cancer and chronic hepatitis C"
Geneviève Inchauspé, PhD
Transgene SA

2009 – 2010

"Innovative Translational Research Studies in HCV-infected People"
Andrew Talal, MD, MPH
Weill Cornell Medical College

"The Liver as a Lymphoid Organ"
Ian Nicholas Crispe, MD, BS, PhD
Seattle Biomedical Research Institute

"Direct Influence of Immunosuppressive Drugs on HCV Replication and Infection"
Sandra Ciesek, MD
Hanover Medical School, Germany

"Characterization of Determinants Important for Glycoprotein Function in Hepatitis C Virus Morphogenesis using Trans-Complementation"
Eike Steinmann, PhD
Hanover Medical School, Germany

"HCV NS5A as an Anti-HCV Target"
Min Gao, MD
Bristol-Myers Squibb Pharmaceutical Research Institute

"Cell-specific Defects in Innate Immunity in Hepatitis C Infection"
Gyongyi Szabo, MD, PhD
University of Massachusetts Medical School

"Chemical Approaches for Dissecting Host-Virus Interactions"
Priscilla L. Yang, PhD
Harvard Medical School

"Hepatitis C Recovery"
David Thomas, MD
Infectious Diseases Viral Hepatitis Center
Center for Global Health
Johns Hopkins University

2008 – 2009

"How Can a Tiny Chimeric Mouse Contribute to The Study of The Hepatitis C Virus?"
Philip Meuleman, Ph.D.
Center for Vaccinology - Ghent University, Belgium

"The Hepatitis C Virus NS5A Protein; New Functions and New Mysteries"
Tim Tellinghuisen, Ph.D.
The Scripps Research Institute, Florida

"Host Factors Supportive of HCV Replication
Ray Chung, M.D.
Massachusetts General Hospital

"Host Factors Involved in The Control of Hepatitis C Virus Infection"
Barbara Rehermann, M.D.
National Institutes of Health, NIDDK

"Future Therapy of Hepatitis C: A Clinical Perspective"
Stefan Zeuzem, M.D.
Goethe University Hospital, Germany

"Pathways of Memory T Cell Differentiation Dduring Viral Iinfection"
Susan Kaech, Ph.D.
Yale School of Medicine

"Structure and Function of The Hepatitis C Virus Replication Complex"
Darius Moradpour, M.D.
University of Freiburg, Germany

"Maintenance Interferon for Hepatitis C"
Anna Lok, M.D., M.R.C.P.
University of Michigan Health System

"Acute hepatitis C in Egypt: epidemiology, natural history and treatment"
Arnaud Fontanet, M.D.
Institute Pasteur, France

2007 – 2008

"Differentiation and Regulation of Antiviral CD8 T Cells"
John Wherry, Ph.D.
The Wistar Institute

"Human NK Cells - Molecular Specificity and Biological Function"
Hans-Gustaf Ljunggren, M.D., Ph.D.
Karolinska Institutet, Sweden

"HCV-specific Lymphocytes: Do They Hide Somewhere?"
Vito Racanelli, M.D.
University of Bari Medical School, Italy

"Discovery of Potent Inhibitors of HCV Replication"
Johan Neyts, Ph.D.
University of Leuven [KULeuven], Belgium

"Finding a Way Through Intercellular Junctions: How Enteroviruses Enter Polarized Cell Monolayers"
Carolyn B. Coyne, Ph.D.
The University of Pittsburgh

"Modeling HIV-1 Infection and Immuno-Pathogenesis in Humanized Mice"
Lishan Su, Ph.D.
University of North Carolina at Chapel Hill

"Hepatocellular Carcinoma: A Growing Complication of Cirrhosis"
Gary Davis, M.D.
Baylor University Medical Center

"RNA Synthesis by Positive-strand RNA Viruses"
Cheng Kao, Ph.D.
Texas A&M University

"The Isolated Human Hepatocyte: A Substrate for Basic Research, Animal Model Development and Clinical Therapy"
Michael Ott, Ph.D.
Hannover Medical School, Germany

"Hepatocellular Carcinoma: An Epidemic?"
Hashem El-Serag, M.D., M.P.H.
Baylor College of Medicine

"Towards a Vaccine for Hepatitis C"
Andreas Cerny, M.D.
University of Bern, Switzerland

"Insights in The Cell Entry Process of The Hepatitis C Virus and Its Modulation by Lipoproteins"
Francois-Loïc Cosset, Ph.D.
Ecole Normale Supérieure de Lyon, France

"Microscale Hepatic Tissue Engineering"
Sangeeta Bhatia, M.D., Ph.D.
Massachusetts Institute of Technology

"Hepatitis C and Insulin Resistance: What is the Significance?"
Stephen Harrison, M.D., L.T.C., M.C.
University of Texas Health Science Center
Brooke Army Medical Center

"Liver Steatosis in Hepatitis C: Mechanisms and Consequences"
Alfredo Alberti, M.D.
University of Padova, Italy

"Characteristics of ITMN-191, an Inhibitor of NS3/4a Protease of HCV"
Scott Siewert, Ph.D.
InterMune, Inc.

"New Insights into Immune Protection Against West Nile Virus"
Mike Diamond, M.D., Ph.D.
Washington University School of Medicine

2006 – 2007

"Hepatic Stellate Cells Express Functional CXCR4: Implications for HIV/HCVmediated Liver Fibrosis"
Meena Bansal, M.D.
Mount Sinai School of Medicine

"Host Factors Influencing the Natural History and Treatment of Chronic Viral Hepatitis’
Howard Thomas, Ph.D., F.R.C.P., F.R.C.Path, F.Med.Sci.
Imperial College London, UK

"Lymphocyte Recruitment to the Liver in Hepatitis C"
David Adams, M.D.
University of Birmingham, UK

"Hepatitis D, from 1977 to 2006"
Mario Rizzetto, M.D.
Universita di Torino, Italy

"High Density Lipoprotein, a Link Between HCV Cell Entry and Neutralization"
Birke Bartosch, Ph.D.
Ecole Normale Supérieure de Lyon, France

"In Vivo and In Vitro Studies on HCV Polymerase Inhibitors"
Daria Hazuda, Ph.D.
Merck Research Laboratories

"Human Lymphotropic Virus Infection of Humanized Mice"
J. Victor Garcia-Martinez, Ph.D.
University of Texas Southwestern Medical Center

"Host Genetic Studies of Hepatitis C"
Thomas O’Brien, M.D., M.P.H.
National Cancer Institute, NIH

"Pestivirus Entry"
Till Rümenapf, D.V.M.
Institut für Virologie, Germany

"Structural Mechanisms of West Nile Virus Neutralization"
Daved Fremont, Ph.D.
Washington University School of Medicine

"The RNA Structural Basis for Internal Translation Initiation"
Jeff Kieft, Ph.D.
University of Colorado School of Medicine

"Application of Functional Genomics to Study HCV–Host Interactions and Liver Disease Progression"
KathieAnne Walters, Ph.D.
University of Washington

"Mechanism of Dengue Virus RNA Synthesis"
Andrea Gamarnik, Ph.D.
Fundación Instituto Leloir, Argentina

2005-2006

"Attempts to illuminate a shady virus: A look at the basic science of the hepatitis C virus"
Andrew Syder, Ph.D.
Center for the Study of Hepatitis C, The Rockefeller University

"HCV therapy: What we know and what we don't know - A clinical primer for scientists"
Ira Jacobson, M.D.
Center for the Study of Hepatitis C, Weill Medical College of Cornell University

"Characterization of the hepatitis C virus NS5A protein"
Timothy Tellinghuisen, Ph.D.
Center for the Study of Hepatitis C, The Rockefeller University

"Probing HCV-host interactions with RNA interference"
Glenn Randall, Ph.D.
The University of Chicago

"Genetic vaccination against HCV: New prospects for prophylaxis and therapy"
Alfredo Nicosia, Ph.D.
Istituto di Ricerche di Biologia Molecolare (IRBM - Merck), Italy

"Hepatitis C clinical case presentations"
Furqaan Ahmed, M.D.
Weill Medical College of Cornell University/NewYork-Presbyterian Hospital

"In vivo studies of hepatitis C and its closest relative GB virus B"
Jens Bukh, M.D.
National Institutes of Health (NIH)

"Chemokines as players in the death and life of hepatocytes"
Jackie Maher, M.D.
University of California, San Francisco

"Sch 503034 HCV protease inhibitor early clinical results"
Janice Albrecht, Ph.D.
Schering-Plough Research Institute

"The peculiar pathway of HCV entry"
Tanya Dragic, Ph.D.
Albert Einstein College of Medicine

"VX-950, a hepatitis C protease inhibitor"
Ann Kwong, Ph.D.
Lindsay McNair, M.D., M.P.H.

Vertex Pharmaceuticals, Inc.

"Intersection of the hepatitis C virus life cycle and lipid biosynthetic pathways"
Sharookh Kapadia, Ph.D.
The Scripps Research Institute

"A look under the hood of the HCV motor: Mechanical behavior of NS3 and NS3/4A"
Anna Marie Pyle, Ph.D.
Yale University

"Production of hepatitis C virus particles as a model system to study hepatitis C"
T. Jake Liang, M.D.
National Institute of Diabetes & Digestive & Kidney Diseases of the National Institutes of Health

"Immune responses in HCV liver disease"
Margaret Koziel, M.D.
Beth Israel Deaconess Medical Center

"Hepatitis B vaccination, hepatitis B and C seropositivity, STIs, and other issues in a network study of Bushwick"
Samuel R. Friedman, Ph.D.
National Development and Research Institute

"Pharmacological reversal of hepatic fibrosis and cirrhosis"
Detlef Schuppan, M.D., Ph.D.
Harvard Medical School

"Pestiviruses - strange enzymes and strategies to survive"
Gregor Meyers, M.D., Ph.D.
Institute of Immunology, Germany

"Mice with chimeric human livers: Small animals with huge applications"
Geert Leroux-Roels, M.D., Ph.D.
Ghent University and Hospital, Belgium

"Packaging, replication and transcription of dsRNA bacteriophage phi6"
Dennis Bamford, Ph.D.
University of Helsinki, Finland

"Alphaviruses: An architectural wonder"
Tuli Mukhopadhyay, Ph.D.
Indiana University

"HCV glycoproteins and virus entry"
Jean Dubuisson, D.V.M., Ph.D.
Institute Pasteur of Lille, France

"Interactions between hepatitis C and nonalcoholic fatty liver disease"
Arun Sanyal, M.D.
Virginia Commonwealth University

"Phosphorylation of the hepatitis C virus NS5A protein: A first step of a long way to go"
Petra Neddermann, Ph.D.
Istituto di Ricerche di Biologia Molecolare (IRBM - Merck), Italy

"Control of viral translation by structured RNAs"
Joseph D. Puglisi, Ph.D.
Stanford University

"From bedside to bench: What can we learn from the therapeutic vaccine trials in hepatitis C?" bition of class II fusion protein"
Margaret Kielian, Ph.D.
Albert Einstein College of Medicine of Yeshiva University

Hepatitis C virus: Viral and cellular factors involved in host/virus interaction"
Kunitada Shimotohno, Ph.D.
Institute for Virus Research, Kyoto University, Japan

"Hijacking the ribosome: Translation initiation by a hepatitis C viral RNA"
Jennifer Doudna, Ph.D.
University of California, Berkeley

"Expression of glutathione peroxidase is inversely correlated to the presence of HCV replicon"
Thomas Herget, Ph.D.
Merck KGaA, Germany

2004-2005

"HCV in HIV, new challenges, new opportunities"
Douglas Dieterich, M.D.
The Mount Sinai Medical Center

"Improving antiviral therapeutics for hepatitis B and C: Scientific and pharmaceutic development issues"
Nat Brown, M.D.
Idenix Pharmaceuticals

"Evolution and immunity during acute and chronic HCV infection"
Stuart Ray, M.D.
Johns Hopkins Hospital

"Do T-cells play a role in HCV infection?"
Georg Lauer, M.D.
The Partners AIDS Research Center

"Lessons from retroviral pseudotypes for hepatitis C virus biology"
Jane McKeating, Ph.D.
Center for the Study of Hepatitis C, The Rockefeller University

"CD1d-reactive NKT cells: Exploiting anti-viral and anti-tumor responses"
Mark Exley, Ph.D.
Harvard Medical School

"HCV and BVDV recruit nuclear factors for replication - a way to counteract the cell's antiviral response?"
Sven-Erik Behrens, Ph.D.
Fox Chase Cancer Center

"Prospects for hepatitis C vaccination"
Mike Houghton, Ph.D.
Chiron Corporation

"Replication of human hepatitis delta virus: Many unique and surprising features"
John Taylor, Ph.D.
Fox Chase Cancer Center

"HIV escape and evolution"
Douglas Richman, M.D.
University of California, San Diego Medical Center - Moores Cancer Center

"Unexpected evolutionary relationships among icosahedral viruses revealed by the birnavirus crystal structure"
Félix Rey, Ph.D.
Centre National de la Recherché Scientifique, France

"The impact of peginterferon and ribavirin dose on the ability to effectively treat chronic HCV infection"
Mitchell Shiffman, M.D.
Virginia Commonwealth University

"The next generation of HCV inhibitors"
George Kukolj, Ph.D.
Boehringer Ingelheim, Canada

"Predictors of response to anti-viral therapy in hepatitis C"
Jenny Heathcote, M.D., F.R.C.P., F.R.C.P.(C)
Toronto Western Research Institute, Canada

"Can high throughput technologies, bioinformatics and liver biopsies unlock the mysteries of hepatitis C virus infection?"
Michael Katze, Ph.D.
Washington National Primate Research Center

"Mechanisms of hepatitis C virus clearance and persistence"
Barbara Rehermann, M.D.
National Institute of Diabetes & Digestive & Kidney Diseases of the National Institutes of Health

"RNA secondary structure and virus persistence"
"Peter Simmonds, B.M., Ph.D., M.R.C.Path.
University of Edinburgh, UK

"Inactivation of hepatitis C virus NS2/3 protease is deleterious for RNA replication"
Arnim Pause, Ph.D.
McGill Cancer Center, McGill University, Canada

"Poliovirus RNA replication: Catalytic lattices on pirated membranes"
Karla Kirkegaard, Ph.D.
Stanford University

"TWEAK, a novel regulator of hepatic progenitor cells"
D. Montgomery Bissell, Ph.D.
University of California, San Francisco

"How RNA viruses evolve and what this means for disease and treatment"
Eddie Holmes, Ph.D.
Pennsylvania State University

"Triggering interferon antiviral immunity: Implications for viral oncolytic therapies"
John Hiscott, Ph.D.
McGill University and Lady Davis Institute, Jewish General Hospital

"Development of targeted therapies for hepatitis C: Current strategies and future challenges"
Raffaele De Francesco, Ph.D.
Istituto di Ricerche di Biologia Molecolare (IRBM - Merck), Italy

"Hepatitis C in injection drug users"
David Thomas, M.D., M.P.H.
Johns Hopkins University, School of Medicine

"Studying acute hepatitis C: What can we learn?"
Prof. Dr. Michael Manns
Medical University Hannover, Germany

"Stealth and cunning: HBV and HCV"
Frank Chisari, M.D.
Scripps Research Institute

"Structure and functions of the flavivirus envelope glycoprotein"
Prof. Franz X. Heinz
University of Vienna, Austria

2003-2004

"Development of a Vaccine Against Hepatitis C Virus: Why and How"
Genevieve Inchauspé, Ph.D.
Unité Mixte CNRS/BioMerieux, France

"New Antiviral Targets in Hepatitis C Virus"
Jeffrey Glenn, M.D., Ph.D.
Stanford University School of Medicine

"HCV Resistance to Antiviral Agents"
Giovanni Migliaccio, M.D., Ph.D.
P. Angeletti, Merck Research Laboratories
Istituto di Ricerche di Biologia Molecolare (IRBM - Merck), Italy

"Memory CD8 T Cell Differentiation Following Acute and Chronic Viral Infection"
E. John Wherry, Ph.D.
Emory Vaccine Center, Emory University

"Immune Control and Immune Failure in HCV Infection"
Bruce D. Walker, M.D.
Partners AIDS Research Center, Massachusetts General Hospital

"The Role of Protein Kinase R in Innate Immunity Signaling"
Bryan Williams, Ph.D.
The Cleveland Clinic Foundation

"Cellular Immunity to HCV"
Xiaosong He, Ph.D.
Stanford University School of Medicine

"The Molecular Pathogenesis of Hepatocellular Carcinoma"
Jack R. Wands, M.D.
Brown University

"Hepatitis C/HIV Coinfection"
Mark Sulkowski, M.D.
Johns Hopkins University School of Medicine

"Translation Control by Cap-Binding Proteins: Implications for Cancer and Memory"
Nahum Sonenberg, Ph.D.
McGill University

"The Host Response to Hepatitis C Virus"
Michael Gale, Jr., Ph.D.
University of Texas

"Hepatitis C and Hepatocellular Carcinoma"
Adrian M. Di Bisceglie, M.D., F.A.C.P.
St. Louis University School of Medicine

"T Cell Response During Acute and Chronic Hepatitis C Virus Infection"
Robert Thimme, M.D.
University of Freiberg, Germany

"A Cellular Chaperone Regulates Polyprotein Processing and Cytopathogenicity of Pestiviruses"
Norbert Tautz, Ph.D.
Justus-Liebig-Universitat Giessen, Germany

"Role of Cell Death in Clearance of Hepatitis B"
William S. Mason, Ph.D.
Fox Chase Cancer Center

"Hepatitis C: Forays into Gene Therapy and RNA Interference Using a SCID Mouse Model"
Christopher D. Richardson, Ph.D.
Ontario Cancer Institute, University of Toronto

"Chronic Hepatitis: Molecular Tale of Two Viruses"
James Ou, Ph.D.
Keck School of Medicine, University of Southern California

"Iron & Hepatitis C"
Bruce R. Bacon, M.D.
St. Louis University School of Medicine

"The Natural and Unnatural History of Hepatitis C Virus Infection: A Clinician's Perspective"
Harvey J. Alter, M.D., F.A.C.P.
National Institutes of Health, Warren G. Magnuson Clinical Center

"Attempts to Identify Cellular Factors Involved in HCV Replication"
Volker Lohmann, Ph.D.
University of Heidelberg, Germany

"Variables Influencing the Natural History of Hepatitis C"
Teresa L. Wright, M.D.
University of California, VAMC

"RNA Interference and its Antiviral Potential"
Raul Andino, Ph.D.
University of California San Francisco

"Internal Ribosome Entry Sites in Viral mRNAs"
Peter Sarnow, Ph.D.
Stanford University School of Medicine

"Recent Advances in Structural Biology of Hepatitis C Virus Proteins"
François Penin, Ph.D.
Centre National de la Recherché Scientifique and Université Claude Bernard de France

"Preclinical Characterization of Type 1 and Type 2 Interferons for the Treatment of Chronic Hepatitis C"
Lawrence Blatt, Ph.D.
InterMune, Inc.

2002-2003

"New Ideas about Hepatitis C Virus IRES Structure and Function"
Hugh Robertson, Ph.D.
Weill Cornell Medical College

"Liver Regeneration and Hepatitis C"
Paul Gaglio, M.D., F.A.C.P.
NewYork Presbyterian Hospital-Columbia University Medical Center

"Mechanisms of Protective Immunity to Hepatitis C Virus Infection"
Naglaa Shoukry, Ph.D.
Children's Research Institute, Ohio State University

"Hepatitis B Viruses: A Triple Threat for Malignant Transformation of Hepatocytes"
Charles Rogler, Ph.D.
Albert Einstein College of Medicine of Yeshiva University

"Role of 3' Nontranslated Segment in Hepatitis C Virus RNA Replication"
Stanley Lemon, M.D.
University of Texas Medical Branch

"Interactions of Hepatitis C Virus Proteins with Host Cell Membranes"
Darius Moradpour, M.D.
University of Freiburg, Germany

"Dengue Virus and Dendritic Cells"
Sarah Schlesinger, M.D.
International AIDS Vaccine Initiative

"Hepatitis C Immunopathogenesis: From Bench to Bedside"
David Nelson, M.D.
University of Florida

"Clinical Research and Hepatitis C: Lessons Learned, Future Directions"
John McHutchison, M.D.
Duke University Medical Center

"Management of Non-Responders to Combination Therapy of Chronic Hepatitis C"
Marc Ghany, M.D.
National Institute of Diabetes & Digestive & Kidney Diseases, National Institute of Health

"The Discovery of BILN 2061 - A Novel HCV protease Inhibitor and the First Small Molecule of its Class with Clinical Proof-of-Concept"
Daniel Lamarre, Ph.D.
Boehringer Ingelheim, Canada

"A Genomic Study of Hepatitis C"
Albert Zlotnik, Ph.D.
EOS Biotechnology

"The Chimpanzee Model of Hepatitis C Virus; Viral Clearance, Microarrays and Protective Immunity"
Robert E. Lanford, Ph.D.
Southwest Foundation for Biomedical Research, Southwest Regional Primate Research Center

"Mode of Induction and Functions of Viral-stress Inducible Genes"
Ganes Sen, Ph.D.
The Cleveland Clinic Foundation

"Molecular Pathogenesis of Hepatic Fibrosis"
David Brenner, M.D.
NewYork Presbyterian Hospital-Columbia University Medical Center

"Pestiviruses - Role of Cellular Sequences in Cytopathogenicity"
Heinz-Juergen Thiel, D.V.M.
Justus-Liebig-Universitat, Germany

"Virus-host Interactions in Picornavirus Replication"
Bert Semler, Ph.D.
University of California Irvine

"Primary Activation of CD8+ T Cells Within the Liver: Consequences and Outcomes"
Patrick Bertolino, Ph.D.
Centenary Institute of Cancer Medicine and Cell Biology, Australia

"In Vivo Regulation of Inflammatory Cell Trafficking through Innate Cytokine/Chemokine Networks"
Thais P. Salazar-Mather, Ph.D.
Brown University

"Replication of the Hepatitis C Virus in Cell Culture"
Ralf Bartenschlager, Ph.D.
University of Heidelberg, Germany

2001-2002

"DC-SIGN and DC-SIGNR: Helping Hands for HIV"
Stefan Poehlmann, Ph.D.
University of Pennsylvania

"HCV Dynamics and Rapid Molecular Evolutionary Genetics During Daily High Dose Interferon and Combination Therapy "
Gerond Lake-Bakaar, M.D., M.R.C.P.
VA Medical Center Northport

"Getting at the Core of Hepatitis C Virus"
John McLauchlan, Ph.D.
University of Glasgow

"Use of Recombinant Vesicular Stomatitis Virus Vectors for Cell-Specific Targeting Approaches"
Michael Whitt, Ph.D.
University of Tennessee Health Sciences Center

"Genomics and the Discovery of a New Protein of the Hepatitis C Virus"
Andrea Branch, Ph.D.
The Mount Sinai Medical Center

"Structural Organization of Alphaviruses and Flaviviruses"
Richard Kuhn, Ph.D.
Purdue University

"Quantitative Phenotypic analysis of Liver-infiltrating Lymphocytes in End-stage HCV Infection"
Judie Boisvert, Ph.D.
Stanford University School of Medicine

"Determinants for Membrane Association of the Hepatitis C Virus Nonstructural Proteins"
Darius Moradpour, M.D.
University Hospital Freiburg

"HCV Replication: What Does It All Mean?"
Keril Blight, Ph.D.
Washington University School of Medicine

"Cryoglobulinemia and Hepatitis C"
Peter Gorevic, M.D.
The Mount Sinai Medical Center

"Mechanism for Recovery from HBV and HCV Infections"
Christoph Seeger, Ph.D.
Fox Chase Cancer Center

"Fatty Liver and HCV"
Zobair Younossi, M.D., M.P.H.
Inova Fairfax Hospital

"Viral Kinetics of the Hepatitis C Virus and Treatment Response"
Jennifer Layden
University of Illinois at Chicago

"Constraints of HCV Evolution"
Jean-Michel Pawlotsky, M.D., Ph.D.
Hôpital Henri Mondor, France

"Hepatitis B-and C-related Liver Carcinogenesis: New Insights from in vivo Tumor Analyses"
Christian Brechot, M.D., Ph.D.
French Institute for Health and Medical Research (Inserm)

"Pharmacokinetics and Pharmacodynamics of PEG-Intron"
Mark Laughlin, M.D.
Schering-Plough Pharmaceuticals

"HCV: What Determines Success and Failure of Immune Responses"
Paul Klenerman, M.B., Ch.B., M.R.C.P.
John Radcliffe Hospital, Oxford England

"ITP and Hepatitis C"
James B. Bussel, M.D.
Weill Medical College of Cornell University

"Inhibition of NK Cells by HCV-E2"
Nick Valiante, Ph.D.
Chiron Corporation

"Amplification and Attenuation of Dendritic Cell responses via Cognate Interactions with Autologous NK Cells"
Nick Valiante, Ph.D.
Chiron Corporation

"Poliovirus Polymerase: Structure, Function and Mechanism"
Craig Cameron, Ph.D.
Penn State University

"Hepatitis C and Fibrosis"
Nezam Afdhal, M.D., F.R.C.P.
Beth Israel Deaconess Medical Center, Liver Center

"Hepatitis C in Children"
Maureen Jonas, M.D.
Harvard Medical School

"Hepatitis C Virus mRNA, Ribonuclease L and Interferon Resistance"
David Barton, Ph.D.
University of Colorado Health Sciences Center

"Substrate Complexes of HCV RNA polymerase: Structural Insights into Nucleotide Import and De-novo Initiation."
Joe Jaeger, Ph.D.
Leeds University

"Hepatic Fibrogenesis: Cell and Molecular Mechanisms-Implications for Therapy"
Don Rockey, M.D.
Duke University Medical Center

"Biogenesis of Hepatitis C Virus Envelope Glycoproteins"
Jean Dubuisson, D.V.M., Ph.D.
Unité Hepatite C, Institut de Biologie de Lille

"Does Hepatitis C Virus like B Cells?"
Lynn Dustin, Ph.D.
Center for the Study of Hepatitis C, The Rockefeller University

2000-2001

"Research Plans for Evaluating the Relationship of B Leucocytes and HCV"
Lynn Dustin, Ph.D.
Center for the Study of Hepatitis C, The Rockefeller University

"Role of T Cells in the Outcome of HCV Infection"
Kyong-Mi Chang, M.D.
University of Pennsylvania and Philadelphia VA Medical Center

"Towards Understanding of the HCV Replication Strategy at the Molecular Level"
Zhi Hong, Ph.D.
ICN Pharmaceuticals Inc.

"Strain Differences in the Immune Response to Replication Defective Adenovirus"
Keith Elkon, M.D.
Hospital for Special Surgery

"Interaction between the Hepatitis C Virus, the Liver and the Immune System"
Xavier Paliard, Pharm.D., Ph.D.,
Chiron Corporation

"The Use of HCV Infectious Clones to Study Persistence and Protection from Infection"
Marion Major, Ph.D.
Center for Biologics Evaluation and Research, FDA

"HCV Clearance"
David L. Thomas, M.D.
Johns Hopkins School of Medicine

"Molecular Mechanisms of Th1 Type Cytokine Gene Expression in Microbial Infections"
Ilkka Julkunen, M.D., Ph.D.
National Public Health Institute of Finland

"Immunopathogenesis of Hepatitis C"
Margaret Koziel, M.D.
Beth Israel Deaconess Medical Center

"The Cellular Immune Responses to the Hepatitis C Virus and its Role in Viral Clearance and Disease Pathogenesis"
Barbara Rehermann, M.D.
National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health

"Novel Mechanisms of Signaling and Growth Regulation in the Liver"
Scott Friedman, M.D.
Mt. Sinai School of Medicine

"An Idiot's Guide to HCV Replication: RNA Structure/Function and the Vitamin B12 Story"
Dr. William Lott
Royal Children's Hospital, Australia

"Dynamics of the Early Cellular Immune Response to the Hepatitis C Virus"
Frank Chisari, M.D.
The Scripps Research Institute

"Why Does Immunity Fail in Chronic Hepatitis C"
Christopher Walker, Ph.D.
The Children's Research Institute and The Ohio State University

"Healing Hepatitis C with Modern Chinese Medicine"
Qingcai Zhang, Lic.Ac., M.D.
Zhang's Clinic, New York

"Stem Cell and Lineage Biology: Relevance to Growth and Tissue-Specific gene expression in Liver"
Lola M. Reid, Ph.D.
UNC School of Medicine